Seroprevalence of herpes simplex virus-2 in kidney transplant recipients: A single-center experience

Khameneh, Z.R and Sepehrvand, N and Taghizadeh Afshari, A and Motazakker, M and Ghafari, A and Masudi, S (2010) Seroprevalence of herpes simplex virus-2 in kidney transplant recipients: A single-center experience. Iranian Journal of Kidney Diseases, 4 (2). pp. 158-161.

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Abstract

Viral infections are a real threat in kidney transplant recipients because of their immunocompromised condition. This study aimed to evaluate herpes simplex virus-2 (HSV-2) seropositivity among kidney transplant recipients. Materials and Methods. Serum samples of 91 kidney transplant recipients from Urmia, Iran, were examined serologically for antibodies against HSV-2 using an enzyme-linked immunosorbent assay. Results. The mean time from transplantation at HSV-2 testing was 5.04 ± 4.45 years. The anti-HSV-2 immunoglobulin G antibody was positive in 5.4% of the kidney transplant recipients. Seropositive patients did not present any clinical manifestations of genital herpes infection. There was no association between HSV-2 seropositivity and age, gender, history of hemodialysis and transplantation, blood transfusion, or immunosuppressive regimen. Conclusions. Seroprevalence of HSV-2 is not high among our kidney transplant recipients. However, it remains a source of concern, considering the compromised immune system in this specific population.

Item Type: Article
Additional Information: cited By 6
Uncontrolled Keywords: herpes simplex virus, kidney transplantation, serologic tests
Subjects: R Medicine > R Medicine (General)
Depositing User: Unnamed user with email gholipour.s@umsu.ac.ir
Date Deposited: 15 Aug 2017 04:47
Last Modified: 17 Feb 2019 06:07
URI: http://eprints.umsu.ac.ir/id/eprint/1218

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