Ansari, M.H.K and Omrani, M and Sayyah, B and Ansari, S.K (2010) Effect of helicobacter pylori infection on the lipid, lipoproteins, apolipoprotein-A1, Lipoprotein (a) and apolipoprotein-B in patients with gastritis. African Journal of Microbiology Research, 4 (2). 084-087.
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Abstract
There are evidences of relationship between chronic infections of Helicobacter pylori (H. pylori) and gastritis in some previous studies. The gastritis caused by H. pylori leads to a change in serum levels of lipids, lipoproteins, apolipoprotein-A1 (Apo-A1), apolipoprotein-B (Apo-B) and lipoprotein-a (Lp(a)). These changes will lead to thrombogenesis and other cardiovascular diseases. The aim of this study is to find out a correlation between lipids profiles and helicobacter gastritis. In this study 20 males and 20 females in age between 30 - 50 years old with gastritis resulting from H. pylori were chosen as patients group. Patients serum levels of Apo-A1, Apo-B and Lp(a) as well as total cholesterol, triglyceride, High density lipoprotein (HDL-C) and Low density lipoprotein (LDL-C) were measured. As control, 26 persons with other types of gastritis (helicobacter negative), without having diseases such as: diabetes, hyperlipidemia, renal failure, liver diseases, with similar age ranges were chosen. Mean levels of total Cholesterol, triglyceride, LDL-C, ApoB lipoprotein and Lp (a), as well as total Cholesterol/HDL ratio and LDL-C/HDL-C ratio in patients with gastritis resulted by H pylori were significantly increased compared to control groups. In addition HDL-C and Apo- A1 lipoprotein were decreased significantly. Therefore it was possible to conclude that H. pylori infection can cause lipid metabolism disorders that may act as risk factors for cardiovascular diseases
| Item Type: | Article |
|---|---|
| Additional Information: | cited By 4 |
| Uncontrolled Keywords: | Gastritis, H. Pylori, lipids, lipoprotein, Apo lipoprotein, Lp (a) |
| Subjects: | R Medicine > R Medicine (General) |
| Depositing User: | Unnamed user with email gholipour.s@umsu.ac.ir |
| Date Deposited: | 15 Aug 2017 05:21 |
| Last Modified: | 25 Jun 2019 03:45 |
| URI: | http://eprints.umsu.ac.ir/id/eprint/1231 |
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