Bahadori, M.B and Valizadeh, H and Asghari, B and Dinparast, L and Bahadori, S and Farimani, M.M (2016) Biological activities of Salvia santolinifolia Boiss. A multifunctional medicinal plant. Current Bioactive Compounds, 12 (4). pp. 297-305.
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Abstract
Salvia species are used traditionally for treatment of many disorders all around the world. Salvia santolinifolia is a medicinal plant, traditionally used for treatment of inflammation, hypercholesterolemia, hemorrhoids and diarrhea. Methods: In this study, antibacterial, antioxidant, toxicity, acetylcholinesterase and �- glucosidase inhibitory activities of several extracts of S. santolinifolia were evaluated. Total phenol and flavonoid contents of the extracts were also determined. Results: The MeOH extract showed high antioxidant activity in DPPH scavenging and ferric reducing power assays. All samples exhibited high acetylcholinesterase (IC50 = 42-89 �g/ml) and �-glucosidase inhibitory activities (IC50 = 24-174 �g/ml). The MeOH extract showed great antibacterial and antifungal activities especially against Bacillus cereus and Candida albicans with MIC values from 10 to 200 �g/ml. Conclusion: Our findings indicated that S. santolinifolia is a rich source of natural compounds with strong antimicrobial, antidiabetic and anti-Alzheimer activities. This plant has great potential for several applications as pharmaceuticals and functional foods.
| Item Type: | Article |
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| Additional Information: | cited By 1 |
| Uncontrolled Keywords: | Salvia, diabetes mellitus, alzheimer, antioxidant, antimicrobial, phenolic compounds. |
| Subjects: | R Medicine > R Medicine (General) |
| Depositing User: | Unnamed user with email gholipour.s@umsu.ac.ir |
| Date Deposited: | 17 Jul 2017 07:20 |
| Last Modified: | 27 Jan 2019 05:31 |
| URI: | http://eprints.umsu.ac.ir/id/eprint/162 |
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