COMPARING THE EFFECT OF INTRACUFF ALKALINIZED LIDOCAINE AND LIDOCAINE ALONE ON POSTEXTUBATION COUGH IN LUMBAR LAMINECTOMY SURGERY

Mahoori, A.R and Sane, SH and Golmohammadi, M and Rezai, H and Mali, Z (2017) COMPARING THE EFFECT OF INTRACUFF ALKALINIZED LIDOCAINE AND LIDOCAINE ALONE ON POSTEXTUBATION COUGH IN LUMBAR LAMINECTOMY SURGERY. The Journal of Urmia University of Medical Sciences, 27 (11). pp. 935-941.

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Abstract

In general anesthesia, patients’ coughing during and after recovery is an important clinical problem with a prevalence of 15% to 45%. This study aimed to evaluate the effects of alkalinized lidocaine or lidocaine alone into the tracheal tube cuff on post-extubation cough in lumbar laminectomy surgery with general anesthesia. Materials & Methods: Ninety patients scheduled for lumbar laminectomy in prone position were enrolled in this randomized double-blind prospective study. After tracheal intubation, the tracheal tube cuff was filled with either an alkalinized 2% lidocaine solution or lidocaine alone or 0.9% saline. A logistic regression comprising the two factors was used for analysis. The incidence of sore throat reported by patients and cough 0, 10 and 30 minutes at recovery after extubation. Results: Intracuff alkalinized 2% lidocaine was superior to lidocaine alone and saline in blunting emergence coughing 10 and 30 minutes at recovery after extubation (P = 0.035- P= 0.005). The incidence of sore throat was significantly lower in the alkalinized 2% lidocaine group at the recovery at 10 and 30 min after extubation(p = 0.001). Conclusion: The present study showed that the intracuff alkalinized 2% lidocaine was superior to lidocaine alone or saline in decreasing the incidence of emergence coughing and sore throat during the recovery room after extubation.

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