INVESTIGATING THE EFFECT OF MULTI-WALLED CARBON NANOTUBES ON BRAIN WAVES IN RATS

The changes of brain waves eventually sub-bands power incidence in the form
of clinical protests. Regarding the use of multi-walled carbon nanotubes in neuroscience, the alpha/
theta power ratio is a reliable scale to measure the disorders associated with learning. The present
study aimed to examine the effect of this substance examined on brain waves and investigated its
possible effect on learning through analysis of brain waves sub-bands.
Material & Methods: In this experimental study, 10 male Wistar rats (300-280 g, 4 to 6 months) were
investigated in one group receiving nanotube. In order to record brain waves, electrodes were
implanted in the frontal and the occipital cortex. Brain signals were recorded 15 minutes before and 15
minutes after injection of 1mg / kg carbon nanotube suspension.
Results: After suspension injection, the power of gamma and theta sub-bands and the power ratio of
theta to alpha sub-bands showed a significant reduction in the after injection intervals compared to
baseline (control) (P <0/001). No significant change was observed in the alpha and beta sub-bands (P>
0/05).
Conclusion: The results of this study showed that multi-walled carbon nanotubes reduce the power of
gamma and theta sub-bands and the power ratio of theta to alpha sub-bands and possibly can lead to
disorders associated with learning and memory