EFFECT OF 8 WEEKS OF RESISTANCE TRAINING WITH AND WITHOUT PORTULACALO SEEDS ON SOME OF LIVER INJURY MARKERS IN WOMEN WITH DIABETES TYPE 2

Salehi, A and Farzanegi, P (2015) EFFECT OF 8 WEEKS OF RESISTANCE TRAINING WITH AND WITHOUT PORTULACALO SEEDS ON SOME OF LIVER INJURY MARKERS IN WOMEN WITH DIABETES TYPE 2. The Journal of Urmia University of Medical Sciences, 25 (11). pp. 968-978.

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Abstract

Diabetes is a metabolic disease that can lead to liver damage through oxidative stress. Regular physical activity and using purslane as a medicinal plant -due to its anti inflammatory compounds- may be effective in reducing injury. So the purpose of this study was to investigate the effects of 8 weeks of resistance training with and without portulacalo seeds on some of liver injury markers in women with diabetes type 2. Materials & Methods: In this study, twenty eight sedentary women with T2DM were randomly assigned to four groups of control, training, supplement and training+ supplement. The resistance training program were carried out using resistance bands of varying types at 40-50% of one repetition maximum (1RM), 3 times a week for 8-wk. Subjects in groups 3 and 4 received 7.5 grams of purslane seeds daily. A fasting blood sample was collected as pretest and post-test, followed by 48 hours of physical inactivity and consumption of portulacalo and 12 hours of fasting. Data analysis was performed with paired t-test and ANOVA. (p ≤0 .05). Result: Eight weeks of the resistance training or portulacalo consumption cause a significant decrease in alanine transaminase (ALT), aspartate transaminase (AST) and alkaline phosphatase (ALP) levels compared to pretest. However, the effectiveness of combination group (training+supplement) is better in the above indicators as compared with the strategies (training or supplement). Also, a significant decrease in ALT, AST and ALP levels were detected in the training or supplement groups, as compared to the control group. Furthermore, there was a significant decrease in ALT, AST levels in training+ supplement group, as compared with the training or supplement groups. Conclusion: Our findings suggested that using non-drug strategy such as resistance trainings and portulacalo seed consumption improves indicators associated with liver damage in women with diabetes type 2.

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