Darabi, E and Morshedi, A and Delirezh, N and Tokmechi, A and Mokarizadeh, A (2014) EFFECT OF PEPTIDOGLYCAN-LIPOPOLYSACCHARIDE ON NITRIC OXIDE PRODUCTION BY RAT MESENCHYMAL STEM CELL (MSC) AND INDUCTION OF APOPTOSIS IN ACTIVATED T CELL WITH MSC. The Journal of Urmia University of Medical Sciences, 24 (12). pp. 996-1004.
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Abstract
Mesenchymal stem cells (MSCs) are adult cells which are identified as nonhematopoietic and pluripotent stem cells. Specific stimulation of toll like receptors on the surface of mesenchymal stem cells could change immune responses of these cells into the pre or antiinflammation phenotype. The aim of this study was to evaluate the effect of peptidoglycanlipopolysaccharide on the polarization of stem cells into the anti inflammation phenotype and apoptosis induction in T cells. Materials & Methods: MSCs were isolated from the femoral and tibial bone marrow and re-suspended in DMEM media, and kept in 5% CO2 incubator at 37
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Toll like receptor’s agonist, Mesenchymal stem cell, Apoptosis, Nitric oxide |
| Subjects: | R Medicine > R Medicine (General) |
| Depositing User: | Unnamed user with email gholipour.s@umsu.ac.ir |
| Date Deposited: | 20 Nov 2017 05:58 |
| Last Modified: | 02 Feb 2019 09:36 |
| URI: | http://eprints.umsu.ac.ir/id/eprint/3322 |
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