INVESTIGATING AND COMPARING THE EFFECTS OF EIGHT WEEKS RESISTANCE AND ENDURANCE TRAINING WITH VITAMIN D3 SUPPLEMENTATION ON INFLAMMATORY CYTOKINES IN OBESE HYPERTENSIVE MIDDLE- AGED MEN

The purpose of this study was to investigate and compare the effects of eight weeks
resistance and endurance training with vitamin D3 supplementation on inflammatory cytokines in obese
hypertensive middle-aged men.
Materials & Methods: Sixty three obese hypertensive middle-aged men (age= 39.85±2.8 years and
BMI= 31.6±1.4 kg/m2) volunteered to participate in this study and were randomly divided into six
groups of resistance training with vitamin D (R+D, N=11), resistance training with placebo (R+P,
N=12), endurance training with vitamin D (E+D, N=9), endurance training with placebo (E+P, N=11),
vitamin D (D, N=10) and control (C, N=10, no intervention). The training protocol consisted of
endurance training with gradually increasing of duration and intensity and resistance training with 80%
of the 1RM, 3 times a week for 8 weeks. The supplement groups consumed daily 3000 IU of vitamin D
and the placebo groups ingested the same amount of maltodextrin. Blood pressure and blood samples
were measured before starting training protocol and 36 hours after last training sessions.
Results: In intervention groups, serum levels of interleukin-8 and interleukin-4 were significantly
decreased and increased, respectively. Also, in training groups, systolic and diastolic blood pressure
were significantly decreased. Moreover, only in the systolic blood pressure there were significant
differences between groups in favor of the E+D group at the post-test.
Conclusion: Implementation of endurance and resistance training with vitamin D3 for 8 weeks caused
to decreases of blood pressure and inflammation in obese hypertensive men, but the effect of endurance
training with vitamin D3 on systolic blood pressure was significantly better.