THE EFFECT OF PERFORAN ON THE MOOD SYMPTOMS OF PREMENSTRUAL SYNDROME

Premenstrual syndrome is a group of cyclic symptoms that occur during the
luteal phase of the menstrual cycle.
Materials & Methods: The study was a randomized, double blinded, placebo- controlled trial, with
two treatment group. The students of this study are divided randomly into two groups of Perforan
group (480 mg) and placebo control group. All the students in this study took drugs during three
subsequent cycles so that each person took two capsules daily in the first cycle for one month. In the
second and third cycles, they took the drugs from eight days before menstruation to two days after it,
and they recorded the severity of the symptoms of her menstruation in the questionnaire of the
symptoms.
Result: The results showed a reduction of symptoms in treatment drug group comparing to the
placebo. So that the mean severity was reported 23.64 in the Perforan group, and 46.37with (p=0.001)
in the placebo group.
Conclusion: Mean severity of mood symptoms premenstrual syndrome has showed that Perforan can
reduce the mood symptoms of premenstrual syndrome more than the placebo group.