Alizadeh, M and Farshid, S and Sadeghzadeh, S and Daneshfar, M and Valizadeh, R and Rahimi, M.M (2017) The effect of Cystatin C in the Prevention of Transplantation Rejection and the Cause of Kidney Failure. American Journal of Surgical Advances. pp. 8-10.
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Abstract
Serum cystatin c is not routinely used in the evaluation of renal function and this may be due to high costs, lack of adequate studies on precision, lack of accessibility and reliability. More kidney transplanted patients before creatinine increasing encounter with decreased performance and go toward rejection without certain actions. This study was aimed to evaluate the effect of cystatin C in the prevention of transplantation rejection. Methods: In this prospective study, cystatin c and GFR of 49 kidney transplanted patients in the third, eighth and fourteenth day were evaluated. The correlation of cystatin C and transplant rejection was investigated with Spearman correlation. Results: In our study, there were statistically signifcant relationship between serum level of cystatin c in third, eighth and fourteenth day with transplant rejection. Cystatin C indicated that was a more sensitive indicator compared with creatinine on the fourteenth day in the event of loss of GFR below than 60. Conclusion: Serum cystatin c as a valuable marker can be an effective predictor marker of renal function decreasing beside creatinine. Due to high cost of measuring kits of serum cystatin c, this marker can be used in high-risk patients with possibility of rejection.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Kidney, Cystatin C, Transplantation, Acute Rejection |
| Subjects: | R Medicine > R Medicine (General) |
| Depositing User: | Unnamed user with email gholipour.s@umsu.ac.ir |
| Date Deposited: | 01 May 2018 06:42 |
| Last Modified: | 26 Jun 2019 05:59 |
| URI: | http://eprints.umsu.ac.ir/id/eprint/4789 |
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