Modeling, solubility, and thermodynamic aspects of sodium phenytoin in propylene glycol–water mixtures

Fathi Azarbaijani, A and Martinez, F and Mabhoot, A and Jouyban, A.G (2016) Modeling, solubility, and thermodynamic aspects of sodium phenytoin in propylene glycol–water mixtures. Journal of Molecular Liquids, 219. pp. 68-73.

[img]
Preview
Text
586.pdf

Download (502kB) | Preview

Abstract

The solubility of sodium phenytoin in binary mixtures of propylene glycol and water at 298.2, 303.2, 308.2, and 313.2 K was measured. The effect of solvent composition on the thermodynamic properties of the dissolution process, including enthalpy, entropy, and Gibbs energy were studied based on van't Hoff analysis and the Gibbs equation. Experimental solubility was determined using the shake-flask method and the resulting data were correlated with the Jouyban–Acree model and with the Jouyban–Acree model in combination with the van't Hoff equation

Item Type: Article
Uncontrolled Keywords: Solubility Sodium phenytoin Solvent mixture Jouyban–Acree model van't Hoff equation
Subjects: R Medicine > R Medicine (General)
Depositing User: Unnamed user with email gholipour.s@umsu.ac.ir
Date Deposited: 09 Sep 2018 05:19
Last Modified: 13 Feb 2019 08:13
URI: http://eprints.umsu.ac.ir/id/eprint/5020

Actions (login required)

View Item View Item