Lipid Profle in Cardiac Syndrome X: Association with Helicobacter pylori

Rasmi, Y and Seyyed Mohammadzadeh, M.H and Shirpoor, A.R and Zeynalzadeh, J and Hajhosseini, R (2016) Lipid Profle in Cardiac Syndrome X: Association with Helicobacter pylori. Journal of Clinical and Diagnostic Research, 10 (7). pp. 7-9.

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Abstract

Chronic inflammation caused by Helicobacter pylori (H.pylori) infection has a pathogenic role in Cardiac Syndrome X (CSX). In addition, it has shown that bacterial infection may affect blood lipids. Aim: To assess if H.pylori affects the level of lipid profle in CSX. Materials and Methods: Eighty-eight CSX patients and 97 healthy controls were enrolled. The Total Cholesterol (TC), Triglyceride (TG), Lipoprotein A (LP{A}), Low Density Lipoprotein (LDL), High Density Lipoprotein (HDL), Apoprotein A1 (APOA1), and Apoprotein B (APOB) was estimated colorimetrically. In addition, the presence of IgG antibody to H.pylori was tested in plasma samples by using enzyme linked immunosorbent assay method. Results: TC, LP{A}, LDL, APOA1 and APOB levels in CSX group were signifcantly higher than those of the control group (p<0.05). But, these parameters in H.pylori positive and H.pylori negative, among CSX and control groups were not signifcant. Conclusion: Increased plasma level of lipid profle and H.pylori infection are associated with CSX; it seems that plasma li

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