Lipid Profle in Cardiac Syndrome X: Association with Helicobacter pylori

Chronic inflammation caused by Helicobacter pylori
(H.pylori) infection has a pathogenic role in Cardiac Syndrome X
(CSX). In addition, it has shown that bacterial infection may affect
blood lipids.
Aim: To assess if H.pylori affects the level of lipid profle in CSX.
Materials and Methods: Eighty-eight CSX patients and 97
healthy controls were enrolled. The Total Cholesterol (TC),
Triglyceride (TG), Lipoprotein A (LP{A}), Low Density Lipoprotein
(LDL), High Density Lipoprotein (HDL), Apoprotein A1 (APOA1),
and Apoprotein B (APOB) was estimated colorimetrically. In
addition, the presence of IgG antibody to H.pylori was tested in
plasma samples by using enzyme linked immunosorbent assay
method.
Results: TC, LP{A}, LDL, APOA1 and APOB levels in CSX group
were signifcantly higher than those of the control group (p<0.05).
But, these parameters in H.pylori positive and H.pylori negative,
among CSX and control groups were not signifcant.
Conclusion: Increased plasma level of lipid profle and H.pylori
infection are associated with CSX; it seems that plasma li