Cancer Phytotherapy: Recent Views on the Role of Antioxidant and Angiogenesis Activities

Nowadays, increases in resistance of tumors to the current therapeutic agents have become a problematic issue. Therefore,
efforts to discover new anticancer compounds with high sensitivity of cancer cells are extending. Animal and laboratory
researches have shown that exogenous antioxidants are able to help prevent the free radical damage associated with the
development of cancer. However, researches in human beings have not demonstrated convincingly that taking antioxidants can
reduce the risk of developing cancer. Angiogenesis is also a natural condition that controls the formation of new blood vessels
from the available vessels. Today, it is believed that most of the cancers have angiogenesis potential and their growth, metastasis,
and invasion depend on angiogenesis. Several compounds with plant origin and with anti-angiogenic properties have been
identified. The aim of this study is to review recently published articles about anticancer drugs obtained from plants with anti
oxidant and anti-angiogenesis properties.