Investigation of Herpes Simplex Virus-2 (Hsv-2) Infection in Coronary Artery Disease Patients (CAD) in Population from Iran

Rostamzadeh Khameneh, Z and Mohammadian, M and Nemati, M and Rostamzade, A.R (2015) Investigation of Herpes Simplex Virus-2 (Hsv-2) Infection in Coronary Artery Disease Patients (CAD) in Population from Iran. Adv. Biores, 6 (6). pp. 74-78.

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Abstract

Recent studies have suggested relationships between herpes simplex virus(HSV-2)infection and coronary artery disease (CAD). Presented study investigated the association between the HSV-2immunoglobulin G (IgG) seropositivity, in angiographically diagnosed coronary disease blood. In order to evaluation of Hsv-2 Infection In CAD Patients blood samples were obtained from 193 CAD patients admitted for coronary angiography because of suspected coronary heart disease. Lipid parameters and blood glucose level (fasting blood glucose and random blood glucose) were determined. Of the 193 CAD patients, 192(99.49%) were positive by an ELISA method for herpes simplex virus-2 antibodies IgG and 1 (0.51%) were negative for Hsv-2IgG. When IgG antibodies were considered, there was significant correlation between biochemical parameters and seropositivity of HSV-2 antibody in CAD patients. In conclusion, HSV-2 infection is more common in CAD patients. Chronic HSV-2 infection may be associated with the development of atherosclerotic coronary disease and viral treatment have effective role in control of advanced heart problems

Item Type: Article
Uncontrolled Keywords: Coronary Artery Disease, herpes simplex virus-2, Iran
Subjects: R Medicine > R Medicine (General)
Depositing User: Unnamed user with email gholipour.s@umsu.ac.ir
Date Deposited: 23 Oct 2018 07:03
Last Modified: 11 Jun 2019 06:15
URI: http://eprints.umsu.ac.ir/id/eprint/5276

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