COMPARISON OF SIMPLIFIED ACUTE PHYSIOLOGY SCORE-III AND MORTALITY PROBABILITY MODEL-III IN NON-TRAUMATIC PATIENTS

Different scoring systems are used in order to assess the functional quality of
intensive care units (ICU) and to predict the required costs and facilities of intensive cares. Variety of
scoring systems has been explained that each has advantages and disadvantages. In this study Simplified
Acute Physiology Score-III (SAPS-III) and Mortality Probability Model-III (MPM-III) were compared.
Materials & Methods: The current cross-sectional study was conducted on 240 non-traumatic patients
admitted at ICU of Al-Zahra Hospital in 2016-17. Patients' information including demographics, mean
of systolic, diastolic and arterial pressure, pulse rate, respiratory rate, temperature, Glasgow Coma
Scale(GCS), WBC, hematocrit, bilirubin, creatinine, arterial blood gas, and the presence of underlying
diseases was gathered from the records for measurement of MPM-III and SAPS-III scores and then they
were compared.
Results: This study was conducted on 240 non-traumatic patients. Discrimination of MPM-III in cutoff
point of 0.17 was 0.83(P<0.001; 95%CI: 0.765-0.898), sensitivity and specificity of this test in
prediction of non-traumatic mortality was 82% and 73%, respectively. Discrimination of SAPS-III in
cut-off of 48.5 was 0.78(P<0.001; 95%CI: 0.72-0.84), while its sensitivity and specificity was 83% and
70%, respectively. Duration of ICU hospitalization (P=0.028 and 0.002) and duration of intubation
(P=0.001 and <0.001) had direct association with mortality based on both scoring systems while total
duration of hospitalization was only significant in SAPSIII (P=0.002).
Conclusion: Comparison of SAPS-III and MPM-III in non-traumatic patients presented a higher
discrimination ability for MPM-III. In addition, findings showed that mortality in MPM-III was in
association with duration of ICU admission and intubation while for SAPS-III, in addition to previous
factors, total duration of hospitalization was associated as well