Probiotics and Metabolic Outcomes of Gestational Diabetes: A Review Article

Dolatkhah, N and Hajifaraji, M (2019) Probiotics and Metabolic Outcomes of Gestational Diabetes: A Review Article. International Journal of Research in Applied and Basic Medical Sciences, 5 (2). pp. 82-97.

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Abstract

Gestational diabetes mellitus (GDM) is the most prevalent metabolic problem of gestation. In contrast to subjects without diabetes, women with GDM are at advanced risk of adverse maternal and fetal consequences without intervention. The current and unanticipated growth in the prevalence of gestational diabetes and the middling outcomes of dietary manipulations could somewhat be because of incuriosity to or failure in changing the different combination and unsuitable intestinal micro flora which happens frequently in the second half of pregnancy particularly when complemented with overweight/obesity. In the range of lifestyle-related aspects, probiotics are suggested as part of a balanced diet, low-cost, feasible and potentially impressive strategy to manage this health problem. The objective of this review paper is to review the related studies pursuant to the significance of probiotics and their impression in prohibition and management of GDM. Electronic search was performed in databases, including Scopus, Science direct, PubMed, Cochrane central, Google Scholar, ISC, Magiran, IranMedex, SID, and MedLib. Evidence proposes that manipulation of gut microbiota during pregnancy by certain probiotics in high risk pregnant women may be of pronounced advantage for better metabolic profile of pregnant women and their offspring

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