The risk factors associated with MERS-CoV patient fatality: A global survey

Ahmadzadeh, J and Mirza Aghazadeh Attari, J and Mohebbi, Iraj and Mirza Aghazadeh Attari, M and Mousavi, S.J and Mobaraki, K (2019) The risk factors associated with MERS-CoV patient fatality: A global survey. Journal Pre-proof(Diagnostic Microbiology & Infectious Disease). pp. 1-18.

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Abstract

Risk factors associated with Middle East respiratory syndrome coronavirus (MERS-CoV) infection outcome were established by analyses of WHO data from September 23, 2012 to 18 June 2018. Of the 2220 reported cases, 1408 cases, including 451 MERS-CoV deaths, were analyzed. The case fatality rate was 32% (95% CI: 29.4–34.5). Compared to MERS patients ≤ 30 years old, those with >30 years had the adjusted odds ratio estimate for death of 2.38 [95% CI: 1.75-3.22]. This index was 1.43 [95% CI: 1.06-1.92] for Saudi patients in comparison to non- Saudi; 1.76 [95% CI: 1.39-2.22] for patient with comorbidity in comparison to those without comorbidity; 0.58 [95% CI: 0.44-0.75] for those who had close contact to a camel in the past 14 days and 0.42 [95% CI: 0.31-0.57] for patients with >14 days with onset of signs and hospital admission compared to patients with ≤14 days.

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