Paclitaxel nano-conjugated to polyhedral oligomeric silsesquioxane (POSS) nanoparticles as a novel water-soluble prodrug

Rezaie, j and Jabbari, E and Akbari, A and Asghari Kalashani, S and Jabbari, N (2022) Paclitaxel nano-conjugated to polyhedral oligomeric silsesquioxane (POSS) nanoparticles as a novel water-soluble prodrug. Materials Letters, 307. pp. 1-4.

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Abstract

Condensed polyhedral oligomeric silsesquioxane (POSS) family of materials are very attractive as a nanoscale
drug delivery system in cancer therapy. This work describes a novel method for conjugation of poorly soluble
anticancer drug paclitaxel (PTX) to octa-aminopropyl polyhedral oligomeric silsesquioxane hydrochloride salt
nanoparticles (OA-POSS NPs). The synthesized nanoconjugate of PTX and

Item Type: Article
Uncontrolled Keywords: Polyhedral oligomeric silsesquioxanes Nanoparticles Paclitaxel Functional Nanoconjugate
Subjects: R Medicine > R Medicine (General)
Depositing User: Unnamed user with email gholipour.s@umsu.ac.ir
Date Deposited: 16 Oct 2021 05:05
Last Modified: 16 Oct 2021 05:05
URI: https://eprints.umsu.ac.ir/id/eprint/6319

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