Treating post-renal transplant surgical site infection with combination therapy: a case study

Hajimohammadi, Kazem and Makhdoomi,, Khadijeh and Esmaeili Zabihi, Roghayeh and Parizad, Naser (2021) Treating post-renal transplant surgical site infection with combination therapy: a case study. Journal of Prescribing Practice, 30 (8).

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Abstract

Surgical site infection (SSI) is one of the most common and debilitating complications of surgery. The risk of SSI rises if the patient has underlying health-related risk factors. This article reports on the complicated case of 61-year-old female with a history of obesity and diabetes. She was diagnosed with end-stage renal disease (ESRD) and had been receiving haemodialysis since 2012. She underwent a kidney transplant and developed a multidrug-resistant Pseudomonas aeruginosa SSI following surgery. She experienced delayed wound healing with a partially dehisced incision. Despite conventional wound care, there was no progress in wound healing. The authors combined sharp debridement, irrigation and antibiotic therapy with a silver-containing antimicrobial dressing for 1 month. Her SSI improved significantly and she returned to theatre for wound closure. The patient recovered well and was discharged from the hospital after suture removal. Wound-care professionals can use combination therapies to manage SSIs effectively and reduce patient and healthcare costs.

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