Toxoplasma gondii exposure and the risk of schizophrenia

Khademvatan, S and Saki, J and Khajeddin, N and Izadi Mazidi, M and Beladi, R and Shafiee, B and Salehi, Z (2014) Toxoplasma gondii exposure and the risk of schizophrenia. Jundishapur Journal of Microbiology, 7 (11).

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Abstract

Schizophrenia is a major psychiatric disorder with a deeply destructive pathophysiology. There are evidences to indicate that infectious agents such as Toxoplasma gondii may play some roles in etiology of the disorder. Objectives: The current study aimed to determine the association between T. gondii exposure and the risk of schizophrenia. Materials and Methods: T. gondii IgG antibodies of 100 patients with schizophrenia as well as 200 healthy volunteers were assessed. The subjects also completed demographic questionnaires. Data was analyzed using the chi-square and Fisher exact tests. Results: The analyses confirmed the significant differences between healthy women and ones with schizophrenia (P = 0.001) as well as between males and females with schizophrenia (P = 0.009) in IgG positivity. Conclusions: The present study supported the contamination with T. gondii as a risk factor for schizophrenia just in women

Item Type: Article
Additional Information: cited By 4
Uncontrolled Keywords: Toxoplasma gondii; Schizophrenia; Toxoplasmosis; Parasite; Enzyme-Linked Immunosorbent Assay; Iran
Subjects: R Medicine > R Medicine (General)
Depositing User: Unnamed user with email gholipour.s@umsu.ac.ir
Date Deposited: 26 Jul 2017 09:43
Last Modified: 06 Apr 2019 05:11
URI: http://eprints.umsu.ac.ir/id/eprint/685

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