Evaluation of relationship between grading of fatty liver and severity of atherosclerotic finding

Purpose: Nonalcoholic fatty liver disease (NAFLD) is a feature of metabolic syndrome and has a high prevalence
in the general population. Objective: To determine the severity of atherosclerotic finding in various grade of
NAFLD. Material and Methods: We examined 250 consecutive patients with various grade of NAFLD and 85 control
subjects matched for age, gender, to determine carotid intima-media thickness (CIMT) in each groups. Results: The
mean CIMT in patients with G1, G2 and G3 NAFLD were 0.78±0.15 mm, 0.82±0.11mm and 0.85±0.16mm respectively.
The differences in CIMT between the various grades of NAFLD were statistically significant (p=0.01). Conclusion:
According to our study results the presence of NAFLD; severity of atherosclerosis will be higher parallel with
severity of fatty liver infiltration. Therefore, Patients with NAFLD especially high-grade fatty liver may be candidate to
be investigated for the presence CAD