The Effect of 8 Weeks Aerobic Training on Angiogenesis (VEGF) and Angiostatic (ES) Factors In Sedentary Women

Tolouei Azar, J and Ravasi, A.A and Soori, R and Akbarnejad, A and Hemati Nafar, M (2017) The Effect of 8 Weeks Aerobic Training on Angiogenesis (VEGF) and Angiostatic (ES) Factors In Sedentary Women. The Journal of Urmia University of Medical Sciences, 27 (12).

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Abstract

It is more important to know which of physical activities could be the most effective way to cause angiogenesis. In this regards, we have investigated an 8-week aerobic training on vascular endothelial growth factor (VEGF) and Endostatin (ES) in sedentary women. Materials & Methods: 20 volunteer inactive women were chosen and were randomly divided in 2 groups of aerobic and control. Aerobic training programme consisted of 3 days per week for 8 weeks, each consists of 30 minutes with intensity of 65-70% of maximum heart rate was performed.. Before and after training, we have tested aerobic training and control group after an overnight fast. Blood Samples were used to conduct Enzyme-linked immunosorbent assay (ELISA). Independent and Dependent T-Test t were performed to see the significance level of (P<0.05. Results: Statistical analysis revealed that aerobic training increased VEGF and decreased ES to a significant level. Consequently, the results of Independent T Test revealed that there is an obvious difference (P<0.05), between the amount of VEGF and ES in control and intervention group. Conclusion:The results show that the equilibrium between angiogenesis and angiostatic agents. As a result, aerobic training is shifted toward angiogenesis factors. This result helps us to understand the process of angiogenesis consistence with aerobic training activities

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