ANTIBIOTICAL RESISTANCE PATTERN OF MICROORGANISMS ISOLATED FROM POSITIVE BLOOD CULTURES AT ICUS OF IMAM KHOMEINI HOSPITAL

Hemmati, A and Nikoonejad, A.R and Lotfollahi, L and Jahed, S and Nejad Rahim, R and Nabizadeh, E (2016) ANTIBIOTICAL RESISTANCE PATTERN OF MICROORGANISMS ISOLATED FROM POSITIVE BLOOD CULTURES AT ICUS OF IMAM KHOMEINI HOSPITAL. The Journal of Urmia University of Medical Sciences, 27 (6). pp. 533-540.

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Abstract

The increasing rate of antibiotic resistant bacteria in different wards of hospitals,
especially in the intensive care units and increasing rates of morbidity and mortality due to these
bacteria, highlights the need for awareness of antibiotic resistance patterns. The aim of this study was
to determine the antibiotic resistance patterns of microorganisms isolated from positive blood cultures
at ICUs of Imam Khomeini Hospital during 2011-2013.
Materials & Methods: This cross-sectional study was done from September 2011 until March 2013 in
Imam Khomeini Hospital in Urmia. During study, positive blood culture specimens of ICU patients
were sent to the laboratory. The evaluated cases were determined for resistance by DDA method. Type
of bacteria and results of antibiogram recorded in testing sheets were collected and the data were
analyzed by SPSS software 20.
Results: Among all blood cultures were carried out in the mentioned period, about 101 positive results
were reported. Among them 56 (55.4%) and 45 (44.6%) were men and women, respectively. Patients'
age ranged from 13 to 94 and the average age of them was 57.8. The most common Gram-positive
bacteria that grew in blood cultures were coagulase negative staphylococci (35.6%) and the most
effective antibiotic against them was vancomycin and the less effective antibiotics were imipenem,
amoxicillin and cephalexin. The most common Gram-negative bacteria isolated was E.coli (19.8%) and
the most effective antibiotics to this microorganism were Ceftazidime and Tetracycline and the less
effective were Cephalexin and Nalidixic Acid.
Conclusion: The results of this study showed that there is significant resistance to most antibiotics used
commonly, perhaps one of the reasons of this reality is massive and incorrect using of antibiotics. It
should be noted that the precise determination of antibiotic resistance pattern requires further study with
more samples in different therapeutic centers and repeating of such assessments periodically

Item Type: Article
Uncontrolled Keywords: Antibiotic resistance, Microorganism, Blood culture, Intensive Care Units
Subjects: R Medicine > R Medicine (General)
Depositing User: Unnamed user with email gholipour.s@umsu.ac.ir
Date Deposited: 23 Sep 2017 07:05
Last Modified: 03 Jun 2019 06:45
URI: https://eprints.umsu.ac.ir/id/eprint/2988

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