ANTIBIOTIC RESISTANCE OF ISOLATED BACTERIAL AGENTS OF CULTURES OF PATIENTS WHO REFERRED TO SHAHID FAGHIHI MEDICAL CENTER OF SHIRAZ

The Present study aimed to detect bacterial agents isolated from culture of
samples that were sent to laboratory of Shahid Faghihi Medical Center of Shiraz and determin their
bacterial resistance.
Materials & Methods: This cross- sectional descriptive study included 1500 culture specimens
consisting of urine, sputum, skin, throat, wound cultures, etc that were sent to laboratory in a five
months period -spring to summer 2006. The positive culture, isolated bacterial agents and antibiogram
test results were recorded in the observation sheet. The collected data were analyzed using SPSS
software, descriptive statistics, and χ² test.
Results: Out of 1500 culture specimen, 502 were positive. 50.8 % of positive cultures belonged to
men and 49.2% to women. Gentamysin(99.8%), Ciprofloxacin (99.6%), and Cephalexin (95, 8%)
were mostly used antibiotics. The bacterial resistance rates were 61.6%, 50.2%, and 94.6%
respectively. The most resistancy to Gentamysine was related to Antrococc (96.7%) and the least was
Ecoli (37.9%). χ ² tests showed that positivite culture and antibiotic resistancy did not have
relationship with patients' sex.
Conclusion: The result showed that the increasing rate of bacterial resistance to current antibiotics are
due to overconsumption. It is suggested to avoid unprescribed use of antibiotics. Further, production
of effective new generation of antibiotics is essential