EFFECT OF INDUCED HYPERCAPNIA ON THE TIME OF EMERGENCE FROM PROPOFOL ANESTHESIA IN ELECTIVE SURGERY

Hosseainzadeh, H and Mohammadi Pouranvari, H and Japarpour, R (2015) EFFECT OF INDUCED HYPERCAPNIA ON THE TIME OF EMERGENCE FROM PROPOFOL ANESTHESIA IN ELECTIVE SURGERY. The Journal of Urmia University of Medical Sciences, Vol. 26(1), March 2015, 26 (1). pp. 39-46.

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Abstract

Hypercapnia cause to increase rate of emergence time from anesthesia and decrease spontaneous breathing onset time and extubation meaningfully. The aim of this study was evaluation of effects induced hypercapnia on emergence from anesthesia with propofol in elective surgery Materials & Methods: In a clinical trial studying that was perforemd in anesthesiology departemnt of Tabriz Univercity on patient that underwent elective surgery, we evaluated the effects of induced hypercapnia on emergence from anesthesia with propofol. Results: Accordinly, 38 patients in normocapnia group and 38 patients in hypercapnia group were evaluated. Average age of patients in normocapnia group was 33±11.27 and in hypercapnia group was 36.94±11.56 years (P=0.134). The Average time of eye opening in patients of normocapnia group was 11.92±1.97 and in hypercapnia group was 7.98±1.74 minutes (P<0.001). The average time of mouth opening in patients of normocapnia group was 12.78±1.90 and in hypercapnia group was 9.30±1.91 minutes (P<0.001). The Averag time of spontaneous breathing in patients of normocapnia group was 9.34±2.40 and in hypercapnia group was 4.53±1.44 minute (P<0.001). The average time of extubation in patients of normocapnia group was 10.76±2.28 and in hypercapnia group was 6.38±1.77 minutes (P<0.001). Conclusion: The Average time of eye and mouth opening, spontaneous starting breathing and extubation in patients of hypercapnia group was significantly lower than normocapnia group.

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