EFFECT OF INDUCED HYPERCAPNIA ON THE TIME OF EMERGENCE FROM PROPOFOL ANESTHESIA IN ELECTIVE SURGERY

Hypercapnia cause to increase rate of emergence time from anesthesia and
decrease spontaneous breathing onset time and extubation meaningfully. The aim of this study was
evaluation of effects induced hypercapnia on emergence from anesthesia with propofol in elective
surgery
Materials & Methods: In a clinical trial studying that was perforemd in anesthesiology departemnt of
Tabriz Univercity on patient that underwent elective surgery, we evaluated the effects of induced
hypercapnia on emergence from anesthesia with propofol.
Results: Accordinly, 38 patients in normocapnia group and 38 patients in hypercapnia group were
evaluated. Average age of patients in normocapnia group was 33±11.27 and in hypercapnia group was
36.94±11.56 years (P=0.134). The Average time of eye opening in patients of normocapnia group
was 11.92±1.97 and in hypercapnia group was 7.98±1.74 minutes (P<0.001). The average time of
mouth opening in patients of normocapnia group was 12.78±1.90 and in hypercapnia group was
9.30±1.91 minutes (P<0.001). The Averag time of spontaneous breathing in patients of normocapnia
group was 9.34±2.40 and in hypercapnia group was 4.53±1.44 minute (P<0.001). The average time of
extubation in patients of normocapnia group was 10.76±2.28 and in hypercapnia group was 6.38±1.77
minutes (P<0.001).
Conclusion: The Average time of eye and mouth opening, spontaneous starting breathing and
extubation in patients of hypercapnia group was significantly lower than normocapnia group.