CORRELATION BETWEEN EMBRYO IMPLANTION AND FOLLICULAR FLUID SELECTED CYTOKINES AND HORMONE LEVELS IN WOMEN UNDER TREATMENT BY MICROINJECTION TECHNIQUE

Ilkhanizadeh, Behrouz and Nahali Moghaddam, Ali and Hajishafiha, Masomeh and Mehrzad Sadaghiani, Mahzad and Nanbakhsh, Fariba and Deldar, Yaghob and Asadi, Nahid and Kiarang, Nazila and Saidi, Vida (2013) CORRELATION BETWEEN EMBRYO IMPLANTION AND FOLLICULAR FLUID SELECTED CYTOKINES AND HORMONE LEVELS IN WOMEN UNDER TREATMENT BY MICROINJECTION TECHNIQUE. The Journal of Urmia University of Medical Sciences, 24 (5). pp. 329-338.

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Abstract

Concentrations of certain substances in follicular fluid (FF) may related to fertilization outcome. The study aim was to identify FF markers with which to predict embryo implantation potential. Materials & Methods: Concentrations of selected hormones, cytokines and growth factors in FF samples obtained during assisted reproduction treatment, Intracytoplasmic Sperm Injection (ICSI) method were related with treatment outcomes. Results: Mean concentrations of 17beta-estradiol (E2), prolactin (PRL) and insulin-like growth factor (IGF)-I were significantly higher, in treatment attempts leading to a clinical pregnancy as compared with those in which no pregnancy was established. LH, growth hormone (GH), progesterone, and interleukin-1 (IL-1) concentrations are similar in successful and unsuccessful attempts. Conclusions: Fertilization outcomes were related to FF levels of PRL, E2 and IGF-I. But LH, growth GH, progesterone, and IL-1 are not markers of success.

Item Type: Article
Uncontrolled Keywords: Implantation, Hormone, Cytokine, Follicular fluid, ICSI
Subjects: R Medicine > R Medicine (General)
Depositing User: Unnamed user with email gholipour.s@umsu.ac.ir
Date Deposited: 28 Nov 2017 05:53
Last Modified: 28 Nov 2017 05:53
URI: http://eprints.umsu.ac.ir/id/eprint/3401

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