Shirpoor, A.R and Taghizadeh Afshari, A and Abdollahzade Fard, A and Rezaee, F (2015) GINGER HYDRO-ALCOHOLIC EXTRACT AMELIORATES THE ALCOHOL-INDUCED KIDNEY DYSFUNCTION IN RAT. The Journal of Urmia Nursing and Midwifery Faculty, 13 (3). pp. 246-252.
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Abstract
Chronic alcohol administration decreases the renal tubular reabsorption and induces renal dysfunction. The association between alcohol consumption and renal function, however, is not very well known. The principal aim of this study was to investigate the effects of chronic ethanol consumption on the functions of the kidney and the possible modification of this effect by ginger extract. Materials &Methods: Twenty-four male wistar rats were divided into three groups namely: Control, ethanol (4.5 gr/kg BW by gavaj), and ginger extract treated ethanolic groups (4.5 gr/kg ethanol along 50 mg of ginger extract). Cystatin c, urea and creatinine in plasma were measured after 42 days. Results: The results revealed that there was a significant decrease in glomerular filtration rate (GFR) and also significant increase in plasma creatinine, urea and cystatin c in ethanol group compared to the control group. Ginger extract treatment improved kidney disfunction induced by ethanol and it may be due to the ginger antioxidant properties. Conclusion: Ginger extract ameliorate kidney dysfunction induced by alcohol
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Ginger, CystatinC, Ethanol, Createnin, Glumerolarfilteration rate. |
| Subjects: | R Medicine > RT Nursing |
| Depositing User: | Unnamed user with email gholipour.s@umsu.ac.ir |
| Date Deposited: | 24 Jan 2018 07:18 |
| Last Modified: | 01 Jul 2019 08:56 |
| URI: | http://eprints.umsu.ac.ir/id/eprint/3942 |
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