EVALUATION OF THE PROPHYLACTIC ANTIBIOTICS EFFECT ON THE LOW-RISK PATIENTS WHO CANDIDATE FOR ELECTIVE LAPAROSCOPIC CHOLECYSTECTOMY

Pourghassem, J and Alilou, L and Pakzad, Sh and Shakibi, A (2013) EVALUATION OF THE PROPHYLACTIC ANTIBIOTICS EFFECT ON THE LOW-RISK PATIENTS WHO CANDIDATE FOR ELECTIVE LAPAROSCOPIC CHOLECYSTECTOMY. The Journal of Urmia University of Medical Sciences, 23 (6). pp. 606-611.

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Abstract

Cholecystectomy is a most known procedure in patients with gallbladder disease such as choleducolithiasis. This study aimed to study the effect of ampibactam prophylaxy (ampicillin/sulbactam) on the low-risk patients who candidated for elective laparoscopic cholecystectomy. Materials & Methods: This clinical double blind work study evaluating the elective laparoscopic cholecystectomy in160 low-risk patients with choleducolithiasis that these patients can consent informed and intentionally between 1389-90. Patients randomly divided in two groups including group A as study group that received 3gr dose of ampibactam (Jaber-ebne-Hayyan Inc) intravenously and group B as control group that received 10cc normal saline (N/S). The information about age, sex, weight, body mass index (BMI), routine tests, hospital stay for all patients was collected. The patients during hospitalization and within 30 days after surgery were followed for incidence of infectious complications. results: According to this study, 1 patient (2/1%) of the intervention group and 2 patients (5/2%) in the control group were infected with the Fisher exact test showed no significant differences between the two groups, and the incidence of infection (4/0 = P). In all three cases (9/1%) had an infection in one patient (6/0%) from the intervention group and 2 patients (3/1%) of the control patients had a skin wound infection (5 / 0 = P). (8/0 = P). The infection complications have seen in one pationet in control group after 6 and in 2 pationts of study group after 5 day after cholecystectom. The mean duration of hospitalization after cholecystectomy in 80 patients in the intervention group was

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