New tetrazolic azo dyes linked to (thio)barbiturate and electron-rich aromatics as potential antimicrobial agents

Pesyan, N.N and Soleimani, D and Jazani, N.H (2015) New tetrazolic azo dyes linked to (thio)barbiturate and electron-rich aromatics as potential antimicrobial agents. Turkish Journal of Chemistry, 39 (5). pp. 998-1011.

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Abstract

A series of new tetrazolic azo dyes based on (thio)barbiturate and electron-rich aromatics were synthesized in excellent yield. The electron-donor and tetrazole ring moieties were linked by a p-phenylazo bridge and the structural characterizations were achieved by FT IR, 1H and 13C NMR, and UV-visible spectrometry. The antibacterial activity of the synthesized compounds was tested against gram-positive and gram-negative bacterial strains, namely Acinetobacter calcoaceticus (ATCC23055), Escherichia coli (ATCC2592), Pseudomonas aeruginosa (ATCC27853), and Staphylococcus aureus (ATCC25923). As a result, potential antimicrobial effects were seen for some of the synthesized compounds.

Item Type: Article
Additional Information: cited By 1
Uncontrolled Keywords: Tetrazole, azo dye, (thio)barbituric acid, antimicrobial effect
Subjects: R Medicine > R Medicine (General)
Depositing User: Unnamed user with email gholipour.s@umsu.ac.ir
Date Deposited: 23 Jul 2017 06:34
Last Modified: 06 Apr 2019 06:34
URI: http://eprints.umsu.ac.ir/id/eprint/471

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