Abdollahzade Fard, A and Makhdoomi, K and Abbasnezhad, P and Saboory, E and Karamdel, H.R and Salehi, M (2017) ASSOCIATION OF SERUM PROLACTIN CONCENTRATIONS WITH RENAL FAILURE IN DIABETIC PATIENTS. Rom J Diabetes Nutr Metab Dis, 24 (3). pp. 179-185.
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Abstract
Diabetes is one of the causes of end-stage renal disease, so that about 70% of all diabetic patients have nephropathy. Prolactin is a hormone that is affected by diabetes but the interaction between diabetes and prolactin has not been understood properly. This study aimed to evaluate the relationship between changes in serum prolactin levels in diabetic patients with renal failure. Material and methods: In this study 223 individuals were participated and after assessment of inclusion/ exclusion criteria 189 individuals were evaluated. Finally, the individuals were divided into three groups: Control (C), Diabetic (D), and Diabetic Nephropathy (DN). Blood samples were collected between 8.00 a.m. and 12.00 a.m. for measurement of prolactin levels and biochemical analysis. Results: The results showed that sodium, potassium, urea, creatinine and prolactin significantly increased in DN group compared to control individuals (P< 0.001). The prolactin levels were significantly decreased in the group of patients with diabetes (P< 0.001). Conclusion: The results of the current study indicated that serum prolactin level decreased in diabetes while it increased in diabetic nephropathy
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | prolactin, diabetes, nephropathy, hemoglobin A1c |
| Subjects: | R Medicine > R Medicine (General) |
| Depositing User: | Unnamed user with email gholipour.s@umsu.ac.ir |
| Date Deposited: | 07 May 2018 04:50 |
| Last Modified: | 10 Jun 2019 07:06 |
| URI: | http://eprints.umsu.ac.ir/id/eprint/4823 |
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