Tasbih Forosh, M and Bahrami Bukani, M and Saboory, E and Zarei, L (2017) Effects of Pulsed Electromagnetic Field with Predatory Stress on Functional and Histological Index of Injured-Sciatic Nerve in Rat. Bull Emerg Trauma, 5 (2). pp. 96-103.
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Abstract
To assess the effect of combination of pulsed electromagnetic felds (PEMF) with predatory stress on transected sciatic nerve regeneration in rats. Methods: In sham- operated group (SOG) the nerve was manipulated and left intact. The 10-mm rat sciatic nerve gap was created in rats. In transected group (Transected) nerve stumps were sutured to adjacent muscle and in vein graft group (VG) the gap was bridged using an inside-out vein graft. In VG/PEMF group the transected nerve was bridged using vein graft, phosphate buffered saline was administered into the graft and the whole body was exposed to PEMF. In VG/PS group the transected nerve was bridged using vein graft, phosphate buffered saline was administered into the graft and the rats underwent predatory stress (PS). In VG/PEMF/PS group the transected nerve was bridged using vein graft, phosphate buffered saline was administered into the graft, the whole body was exposed to PEMF and the rats underwent predatory stress. The regenerated nerve fbers were studied within 12 weeks after surgery. Results: Functional, gastrocnemius muscle mass fndings and morphometric indices confrmed faster recovery of regenerated axons in VG/PEMF and VG/PEMF/PS groups compared to those in the other groups (p=0.001). The whole body exposure to PEMF improved functional recovery. Predatory stress did not affect nerve regeneration in the animals undergone predatory stress (p=0.343). Conclusion: Pulsed electromagnetic felds could be considered as an effective, safe and tolerable treatment for peripheral nerve repair in clinical practice.
| Item Type: | Article |
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| Uncontrolled Keywords: | Nerve regeneration; Sciatic; PEMF; Predatory stress; Functional recovery |
| Subjects: | R Medicine > R Medicine (General) |
| Depositing User: | Unnamed user with email gholipour.s@umsu.ac.ir |
| Date Deposited: | 14 Jul 2018 07:18 |
| Last Modified: | 27 Jan 2019 07:39 |
| URI: | http://eprints.umsu.ac.ir/id/eprint/4941 |
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