The Effect of Pregabalin on the Prevention of Succinylcholine-Induced Fasciculation and Myalgia

Sane, SH and Kazemi Haki, B and Rajabzadeh, M and Golabi, P and Gholamveisi, B and Aghdashi, M.M (2020) The Effect of Pregabalin on the Prevention of Succinylcholine-Induced Fasciculation and Myalgia. Journal of PeriAnesthesia Nursing. pp. 1-5.

Preview

Text 1740.pdf Download (373kB) | Preview

Abstract

This study evaluates the effect of pregabalin on fasciculation and myalgia after using succinylcholine. Design: This randomized double-blind prospective study was conducted among 100 patients aged 20 to 60 years old. Methods: Pregabalin (300 mg) and placebo (in capsule form) were placed in similar containers. The results were analyzed by SPSS 23 software, and statistical analysis consisted of c 2 test and t test, and a P value less than .05 was considered significant. Findings: The mean pain score in the group receiving pregabalin was lower than the placebo group. According to the c 2 test, there was a significant difference between the two groups in the frequency of fasciculation (P ¼ .003). Mean fasciculation severity in the pregabalin group was lower than placebo group. According to t test, there was a significant difference in the mean fasciculation severity between the two groups (P ¼ .002). Conclusions: This study showed that 300 mg of pregabalin was effective in reducing postoperative fasciculation and myalgia in patients treated with succinylcholine

Actions (login required)

View Item