COMPARISON OF HEMODYNAMIC CHANGES DUE TO INTRAVENOUS OXYTOCIN INFUSION DURING GENERAL AND SPINAL ANESTHESIA IN ELECTIVE CESAREAN SECTION

Karami, N and Shabani, A and Sane, SH and Hassani, E (2020) COMPARISON OF HEMODYNAMIC CHANGES DUE TO INTRAVENOUS OXYTOCIN INFUSION DURING GENERAL AND SPINAL ANESTHESIA IN ELECTIVE CESAREAN SECTION. Studies in Medical Sciences, 30 (11). pp. 883-894.

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Abstract

Postpartum hemorrhage is one of the life-threatening complications after labor and cesarean section. Its prevalence is 6 percent. Metratonia is the most common cause of this complication. Some medications can prevent it. Oxytocin is the most common uterine vasoconstrictor and is used routinely after delivery for decreasing hemorrhage. The aim of this study is to compare hemodynamic changes of oxytocin infusion under general anesthesia with spinal anesthesia in elective cesarean section. Materials & Methods: In this observational study, 120 pregnant patients with ASA I and II candidate for elective cesarean section were enrolled in two groups randomly. In one group, general anesthesia and in the other group spinal anesthesia was performed. The heart rate, systolic, diastolic, and mean arterial pressure of patients were recorded every minute until delivery. After umbilical cord clamping and infusion of 30 units dose of oxytocin, the hemodynamic parameters were evaluated every 3 minutes for 30 minutes. Results: Until the delivery, the heart rate, systolic, diastolic, and mean arterial pressure of patients were higher in the general anesthesia group (p=0.002). After beginning oxytocin infusion, these parameters were different in two groups and were higher in the group under general anesthesia. But only the difference of systolic blood pressures was significant (p=0.01) Conclusion: We can conclude that in the cesarean section, the type of anesthesia impression on hemodynamic changes due to oxytocin infusion is only observed on systolic blood pressure and there is no significant difference in other hemodynamic parameters.

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