COMPARISON OF HEMODYNAMIC CHANGES DUE TO INTRAVENOUS OXYTOCIN INFUSION DURING GENERAL AND SPINAL ANESTHESIA IN ELECTIVE CESAREAN SECTION

Postpartum hemorrhage is one of the life-threatening complications after labor
and cesarean section. Its prevalence is 6 percent. Metratonia is the most common cause of this
complication. Some medications can prevent it. Oxytocin is the most common uterine vasoconstrictor
and is used routinely after delivery for decreasing hemorrhage. The aim of this study is to compare
hemodynamic changes of oxytocin infusion under general anesthesia with spinal anesthesia in elective
cesarean section.
Materials & Methods: In this observational study, 120 pregnant patients with ASA I and II candidate
for elective cesarean section were enrolled in two groups randomly. In one group, general anesthesia
and in the other group spinal anesthesia was performed. The heart rate, systolic, diastolic, and mean
arterial pressure of patients were recorded every minute until delivery. After umbilical cord clamping
and infusion of 30 units dose of oxytocin, the hemodynamic parameters were evaluated every 3 minutes
for 30 minutes.
Results: Until the delivery, the heart rate, systolic, diastolic, and mean arterial pressure of patients were
higher in the general anesthesia group (p=0.002). After beginning oxytocin infusion, these parameters
were different in two groups and were higher in the group under general anesthesia. But only the
difference of systolic blood pressures was significant (p=0.01)
Conclusion: We can conclude that in the cesarean section, the type of anesthesia impression on
hemodynamic changes due to oxytocin infusion is only observed on systolic blood pressure and there is
no significant difference in other hemodynamic parameters.