Karimi, N and Hassan, Z.M and Rasuli, M.B and Ilkhanizadeh, B and Salarilak, S and Shahabi, SH (2009) The role of endogenous opioids in the protective effects of local sublethal hyperthermia against the progression of burn injury. Journal of Thermal Biology, 34 (6). pp. 286-289.
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Abstract
The aim of the present study was to evaluate the role of endogenous opioids in local sublethal
hyperthermia-induced protection against burn injury.
Second-degree burn wounds were induced on the back of Balb/c mice. Progression of burn injury
and expression of heat shock protein (HSP)-70 were evaluated after 24 h.
Both inhibition of HSP synthesis and blocking opioid receptors before applying local sublethal
hyperthermia decreased the protective effects of sublethal hyperthermia against the progression of
burn injury. Blocking opioid receptors attenuated induction of HSP-70 by sublethal hyperthermia
| Item Type: | Article |
|---|---|
| Additional Information: | cited By 2 |
| Uncontrolled Keywords: | Sublethal hyperthermia Thermotolerance Burn Endogenous opioids HSP-70 |
| Subjects: | R Medicine > R Medicine (General) |
| Depositing User: | Unnamed user with email gholipour.s@umsu.ac.ir |
| Date Deposited: | 16 Aug 2017 04:38 |
| Last Modified: | 18 Sep 2019 08:08 |
| URI: | https://eprints.umsu.ac.ir/id/eprint/1292 |
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