Pirhayati, F.H and Shayanfar, A and Fathi Azarbaijani, A and Martinez, F and Sajedi Amin, S and Jouyban, A (2017) Thermodynamic solubility and density of sildenafil citrate in ethanol and water mixtures: Measurement and correlation at various temperatures. Journal of Molecular Liquids, 225. pp. 631-635.
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Abstract
Solubility of sildenafil citrate (SC) in binary aqueous mixtures of ethanol (EtOH) were studied
at 293.2, 298.2, 303.2, 308.2 and 313.2 K. Density of the SC saturated solutions over the entire
solvent composition and temperature range was measured using a pycnometer. The effect of
solvent composition on solubility, enthalpy, entropy and Gibbs energy were studied according
to van’t Hoff and Gibbs equations. The experimental solubility and densities were used to
estimate solubility in the investigated solvent system using the van’t Hoff and Jouyban-Acree
model.
| Item Type: | Article |
|---|---|
| Additional Information: | cited By 1 |
| Uncontrolled Keywords: | Solubility, density, sildenafil citrate, solvent mixture, Jouyban-Acree model, van’t Hoff equation. |
| Subjects: | R Medicine > R Medicine (General) |
| Depositing User: | Unnamed user with email gholipour.s@umsu.ac.ir |
| Date Deposited: | 17 Jul 2017 06:13 |
| Last Modified: | 13 Feb 2019 08:03 |
| URI: | https://eprints.umsu.ac.ir/id/eprint/143 |
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