STUDY OF SERUM LEVELS OF VITAMIN D, CALCIUM AND PARATHYROID HORMONE IN PATIENT WITH TUBERCULOSIS AND COMPARISON WITH CONTROL GROUP (A CASE CONTROL STUDY)

Numerous studies showed that vitamin D has direct effect on the innate and
acquired immune system. Serum levels of vitamin D play an important role in the incidence of
infectious disease and also the outcome of its treatment.
Materials & Methods: In this observational and cross-sectional study, the serum levels of vitamin D,
calcium, and, PTH in 44 patients with different forms of tuberculosis were compared with the control
group.
Results: In this study serum level of vitamin D in patients (mean 15.07± 15.99) was significantly
lower than the control group (mean: 16.88±9.88) (p = 0.05). Serum level of calcium in patients group
(9.15±0.59) was significantly (P < 0.001) lower than the control group (9.53 ± 0.26). Serum level of
PTH in patient group (33.08 ± 21.73) did not have significant difference with the control group (38.2 ±
19.1) (p = 0.178).
Conclusion: According to this study low serum level of vitamin D and calcium may be a risk factor
for reactivation of TB in some patients