EVALUATION OF FREQUENCY OF ORAL MANIFESTATION IN END STAGE RENAL DISEASE PATIENTS UNDERGOING HEMODIALYSIS IN IMAM KHOMEINI HOSPITAL IN URMIA

Renal disorders can occur due to several conditions such as diabetes mellitus and
hypertension, thus hemodialysis, dialysis, and renal transplantation are the ways that can help patients.
Considering increasing rate of survival rate in these patients, disorders of oral cavity can lead to low
quality of life and can affect the patient’s general health. The aim of this study was to evaluate,
frequencies of manifestations like, xerostomia, uremic fetor, mucosal ulcers, dental decays, dental
erosions and candidiasis in patients under hemodialysis in Urmia Imam Khomeini hospital.
Materials & Methods: In a descriptive study, 80 consecutive End Stage Renal Disease patients that were
under hemodialysis in Urmia Imam Khomeini Hospital were evaluated. Disease related data such as
length of disease, length of dialysis and underlying cause of disease were gathered. Thus, the patients
went under specific oral examinations for oral manifestations of the disease.
Results: Among patients, in 35% of cases diabetes,40% hypertension,0% glomerulonephritis, 5%
pyelonephritis, 2.5% polycystic kidney disease, and 17.5% others were counted as the underlying
disease. During the specific examinations, in 62.5% of patients, xerostomia, 67.5% uremic fetor, 25%
mucosal ulcer, 50% dental decay, 60% dental erosion and 5% candidiasis were found. Also, the relation
between the oral manifestations and underlying disease were evaluated and P-value for xerostomia was
0.234, uremic fetor 0.05, mucosal ulcer 0.264, dental decay 0.003, erosion 0.082 and candidiasis 0.839.
Conclusion: Chronic and advanced dysfunction of kidney can lead to changes in oral cavity such as,
xerostomia, uremic fetor, mucosal ulcers, dental decays, dental erosions and candidiasis. Though, ESRD
patients should go under periodical examinations for aforementioned oral manifestations and in the cases
of occurred complications, concise treatment should be considered. Further studies for finding other oral
manifestations of ESRD patients are suggested