PREVALENCE OF ACUTE RENAL FAILURE IN THE NEWBORNS WITH JAUNDICE CAUSED BY DEHYDRATION ADMITTED TO NICU OF GHAEM HOSPITAL

Dehydration can lead to exacerbation of Jaundice and renal failure (ARF). It
may also be associated between renal failure and jaundice. One of the common causes of ARF and
jaundice is inadequate breastfeeding. The purpose of this study was to evaluate the relationship
between dehydration resulting from inadequate Breastfeeding and Clinical course of jaundice and
prenatal azotemia in newborns.
Materials & Methods: This descriptive-analytic study was conducted during the period 2006-2012 on
282 hospitalized infant with Jaundice. The study population included all infants with jaundice
admitted to the neonatal intensive care unit of Ghaem hospital that renal function tests were performed
on them. Experimental group (141 infant) include of neonates with serum creatinine level >1.2 mg/dl
and the serum urea level > 40 mg/dl and lower than this values were in the control group (141 infant).
T-Test, Mann-Whitney, chi-square and Roc curve were used to analyze the data.
Results: Fourteen percent of neonatal jaundice had ARF. The most common symptoms at presentation
after Jaundice in case group was Hyperthermia, weight loss, irritability, poor feeding and in control
group was Jaundice. The weight loss>%10 properly diagnosed more than 86% of case group and 78%
of neonates in control group. The weight loss > 7%, properly diagnosed over 75% of neonates with
ARF and 80% healthy infants.
Conclusion: Neonatal jaundice must be monitored weight loss and its effects.Hyperbilirubinemia
infants with restless or hyperthermia must be evaluated from weight loss. Evaluation of renal failure is
necessary in weight loss >%7