PLASMA VISFATIN LEVELS IN WOMEN WITH TYPE 2 DIABETES: COMPARE THE EFFECT OF AEROBIC AND RESISTANCE TRAINING

visfatin is a protein with insulin-like functions that secretes from adipose tissue and has
been linked to obesity and insulin resistance, but the effect of exercise training on visfatin levels is
unknown. The purpose of study was to compare the effect of aerobic and resistance training on plasma
visfatin levels in type 2 diabetic women.
Material and Methods: 45 women with type 2 diabetes were selected by purposive sampling and
subjects were randomly assigned in 3 groups.15 subject participated in an aerobic training (3
days/week, 20-50 min/day, 60-80% maximum heart rate), 15 subject participated in a resistance
training (3days/week, 60 min/day,3 sets of 10 repetition,50-65% 1RM), and 15 subject were in control
group who did not participate in any exercise program during the study periode. blood samples were
collected for assess plasma visfatin, insulin, HbA1c and glucose levels before anf after 12 weeks of the
training program and insulin resistance was calculated with HOMA-IR equation.
Result: Data analysis showed that aerobic training leads to significant decrease in visfatin
concentration (p=0/04), whereas resistance training enhanced visfatin concentration (p=0/13). Also
there was a significant decrease in glucose, HbA1c, insulin resistance, body mass index, waist-hip
ratio and %body fat in experimental groups as compared with control group (p�0/05).
Conclusion: The aerobic exercise training-induced reduction of plasma visfatin is most likely the
result of decrease in Anhtropometric and Glycemic indices and nonsignificant enhance insulin levels
in type 2 diabetes women