EFFECT OF INTERVAL ENDURANCE TRAINING PROGRAM ON PLASMA EOTAXIN,ADIPONECTIN LEVELS , INSULIN RESISTANCE, SERUM LIPID PROFILE AND BODY COMPOSITION IN OVERWEIGHT AND OBESE ADOLESCENTS

Eotaxin is an important chemokine in asthma prevalence and adiponectin, with
anti-inflammatory properties, acts as an agent that can decrease the risk of diabetes and cardiovascular
diseases. The purpose of this study was to examine the effect of eight weeks of interval endurance
training on plasma eotaxin, adiponectin levels, insulin resistance, serum lipid profile, and body
composition in overweight and obese adolescents
Materials & Methods: In this semi-experimental study, 36 healthy overweight and obese male
adolescents were randomly assigned to training (N=18) and control group (N=18). The training group
underwent eight weeks of interval endurance training program (40 min/d, 4 d/wk). Adiposity, insulin
resistance, lipid profile, eotaxin, and adiponectin were measured before and after the completion of
exercise training. To evaluate the results, Paired T-test, Pearson correlation coefficient, and Stepwise
multiple regression analysis were used.
Results: The results showed that eight weeks of interval endurance training decreased the body
weight, body fat percent, BMI, Insulin resistance, waist circumference, and triglycerides levels in
training group (p<0.05), without changes in eotaxine and adiponectin levels (p>0.05).also there was a
significant and positive relationship between eotaxine with cholesterol and LDL levels following
training (p<0.05). Moreover, stepwise multiple regression analysis show that there was a significant
relationship between eotaxin and insulin resistance (p<0.05).
Conclusions: After eight weeks of interval endurance training, without changes in eotaxine and
adiponectin levels decreased triglyceride, insulin resistance and central obesity in overweight and
obese adolescents