EVALUATION AND COMPARING OF QUALITY OF LIFE IN PATIENTS WITH MAJOR DEPRESSION AND BIPOLAR MOOD DISORDER IN PARTIAL RECOVERY PHASE WITH NORMAL INDIVIDUALS

Mood disorders including major depression (MD) and bipolar mood disorders
(BMD) are among the most frequent psychological problems all over the world. Quality of life (QOL)
is an important endpoint to assess the efficacy of treatment in these two conditions. This study aimed
at evaluating and comparing the QOL in these two groups in the partial recovery phase with normal
counterparts.
Methods & Materials: In the analytic-descriptive cross-sectional setting, 20 patients with MD in
partial recovery phase, 20 patients with BMD in partial recovery phase and 20 healthy subjects were
recruited in Tabriz Teaching Razi Centre in a 6-month period of time. Cases with depression score>18
(according to the Beck depression inventory-2; BDI-2) were excluded. The QOL was assessed by the
(World health organization quality of life (WHOQOL-BREF) questionnaire.
Results: The three groups were matched for age and gender. The mean BDI-2 score was significantly
higher in the MD group than that in the two others. The mean score of physical health domain was
significantly lower in the MD group comparing with that in the controls. The mean score of
psychological domain was significantly lower in the MD group comparing with that in the BMD
group. The other scores were comparable between the three groups.
Conclusion: Based on our findings, the QOL was lower in the MD group in partial recovery phase in
some domains comparing with the BMD group in the partial recovery phase and the controls. The
QOL was not significantly different between the BMD group in the partial recovery phase and the
controls.