ASSESSMENT OF THE COMORBIDITY AND ANTICOAGULATION THERAPY IN PATIENTS WITH NON-VALVULER ATRIAL FIBRILLATION ADMITTED TO SEYYED ALSHOHADA HOSPITAL

Atrial fibrillation is common comorbid condition in admitted patients. And it is
the most important risk factor in ischemic stroke in patient with AF. This study aims to assess the
comorbidity and anticoagulation therapy in patients with non-valvuler Atrial Fibrillation admitted to
Seyyed Alshohada Hospital.
Materials & Methods: From 434 admitted patients in Urmia Seyyed Alshohada Hospital from oct.
2009 to mar. 2011, 180 patients (mean age 66.8 ±12.97, 48.3% male) having non-valvular AF were
entered in our retrospective study. On discharge, these patients were evaluated according to anti
coagulation prescription based on CHADS2 scoring.
Results: Assessment of comorbidities of AF in our patients were: HTN with 78.3%, DM with 18.9%,
HF with 11.1%, and stroke with 6.7%.
In our patients 29.5% with CHADS2 score = 0, 62.5% with CHADS2 score = 1, and 61.2% with
CHADS2 score � 2 were on anticoagulation therapy and 100% of patients were taking aspirin at
discharge time. 26.7% out of 57% of total patients who discharged with one oral anticoagulant had
2<INR<3, and 73.3% of these patients had INR 2 or INR 3.The data analysis showed that on the
patients with CHADS2 score � 2, the anticoagulant prescription in patients with AF is independent
from age and other comorbid disorders (such as: HTN, HF, DM and Stroke). But there is a meaningful
difference between anticoagulant prescription, and sex. So that, 72% of women patients and 48.5% of
men patients were received anticoagulant therapy. (p- Value= 0.028)
Conclusion: Our study suggests anticoagulation therapy in patients with AF; it also suggests the
frequent control of side-effects of medication