New tetrazolic azo dyes linked to (thio)barbiturate and electron-rich aromatics as potential antimicrobial agents

A series of new tetrazolic azo dyes based on (thio)barbiturate and electron-rich aromatics were synthesized
in excellent yield. The electron-donor and tetrazole ring moieties were linked by a p-phenylazo bridge and the structural
characterizations were achieved by FT IR, 1H and 13C NMR, and UV-visible spectrometry. The antibacterial activity of
the synthesized compounds was tested against gram-positive and gram-negative bacterial strains, namely Acinetobacter
calcoaceticus (ATCC23055), Escherichia coli (ATCC2592), Pseudomonas aeruginosa (ATCC27853), and Staphylococcus
aureus (ATCC25923). As a result, potential antimicrobial effects were seen for some of the synthesized compounds.