Response of Leptin and C-reactive Protein Serum Levels to 12 Weeks Moderate Intensity Aerobic Exercise in Obese Men

The aim of this study was to investigate the effect of 12 weeks moderate intensity aerobic exercise on leptin and C-reactive protein serum levels in obese
men. The study was conducted in Urmia- Iran in 2015. Twenty-four obese men with
an aged range 40-50 yrs. were enrolled into the study. Subjects were randomized to
one of 2 groups exercise (n=12) and control groups (n=12). The exercise group performed aerobic exercise training up to 50-70 % heart rate reserve, three times a week
for 12 weeks. Leptin and CRP serum level was measured by ELISA method before
and after the 12 weeks. After 12 weeks exercise training, leptin and CRP serum level
in the exercise group compared to the control group, were decreased significantly
(P<0.05). To sum up, 12 weeks moderate intensity aerobic exercise in the reduction of
CRP and leptin concentration had a prominent role that might be effective in reducing
weight and improving cardiovascular risk factors