Severe Anemia and Helicobacter Pylori Infection in school age Children; A case reports

Iron-deficiency anemia is a widespread
public health problem with major
consequences for human health especially,
children. However, in a fraction of patients
an underlying cause is never found during
routine investigation. Recent studies have
suggested an association between
Helicobacter pylori (H. Pylori) infection
and iron-deficiency anemia.
Case presentation
Here is reported four school aged children
(two male, two female) with refractory
severe iron-deficiency anemia associated
H. Pylori gastritis. Mean age of the
patients was 13.62 years old and they were
admitted with chief complaints of
abdominal, chest pain weakness, headache
and respiratory distress.
Mean hemoglobin level in patients was 6.2
g/dl with persistence to iron therapy. After
the diagnosis and therapy of H. pylori
infection, clinical complaints, hemoglobin
level and iron profiles were being normal
and they gained weight.
Conclusion
This study suggests screening of H. pylori
infection and appropriate treatment in any
case of refractory moderate to severe irondeficiency anemia, especially with clinical
manifestations of gastrointestinal tract in
children