The effect of a blue enriched white light on salivary antioxidant capacity and melatonin among night shift workers: a field study

Because of their positive impact on individuals’ performance and alertness, blue enriched white light
sources are gaining popularity in households and industries. However, these sources of blue light spectrum may
cause oxidative stress. On the other hand, there are no empirical studies investigating the negative effect of blue
enriched white light on oxidative stress. Thus, the current study aimed at empirical assessment of the effect of such
light sources on oxidative stress among night shift workers.
Methods: The study, which adopted a cross-sectional design, focused on 30 control room operators of a
petrochemical complex. The subjects followed a shift-work schedule comprising 7 night shifts, 7 day shifts, and
7 days off. The subjects were exposed to 6500 K, 3000 K, and 17,000 K light sources (which have various degrees of
blue light) during three consecutive work cycles, with each cycle lasting for 7 nights. In each light condition, three
salivary measurements were conducted (at the beginning, in the middle, and at the end of the shift). The
measurements were used to assess catalase (CAT), total thiol molecules (TTG), and total antioxidant capacity
(TAC), and melatonin.
Results: The results of repeated measures ANOVA showed that there was no significant difference among various
light conditions with regard to salivary biomarkers (catalase, total thiol molecules, and total antioxidant capacity).
There was however a significant difference between 3000 K and 17,000 K conditions with regard to the
concentration of salivary melatonin (p = 0.001).
Conclusion: Given that there was no significant difference among various light conditions in terms of biomarkers, it
is concluded that using sources of light with high color temperature can be recommended. Nonetheless, because
of the limitations of the present study (e.g. short period of intervention), it is suggested that care should be
exercised in using such light sources.