THE EFFECT OF COOLED HEMODIALYSIS FLUID ON THE ADEQUACY OF DIALYSIS: A CLINICAL TRIAL

The use of cold hemodialysis began in 1980 as an attempt to control hypotension
during hemodialysis and after these years the researchers realized that Cold hemodialysis not only
reduces the periods of hypotension during hemodialysis, but also has other beneficial effects on the
adequacy of dialysis, overall health, and quality of life.
Materials & Methods: This randomized, double-blind, cross-sectional clinical study was carried out at
Zanjan University of Medical Sciences. A total of 42 hemodialysis patients were divided into two
groups: 20 (first group) and 22 (the second group). Then, the first group received standard hemodialysis
(hemodialysis temperature 37 ° C for 4 weeks) and simultaneously the second group received cold
hemodialysis (hemodialysis temperature 35 ° C) for 4 weeks, then the type of group hemodialysis was
changed. The degree of adequacy of dialysis patients was performed on a monthly basis for three times
(before the start of the study, after the first and second 4 weeks) and the data which was available in the
hemodialysis computer system of Vali-e-Asr Hospital in Zanjan was calculated using the Ministry of
Health's proposed software.
Results: The results showed that mean KTV in cold and standard stage was 1. 71 and 1. 46, respectively
and after the second four weeks the mean KTV in cold and standard stage was 1. 69 and 1. 32,
respectively. Cold Hemodialysis significantly improved KTV level (P <0. 001). After the first four
weeks, the mean URR in the cold and standard phase was 76. 30 and 66. 14, respectively, and after the
second four weeks, mean URR in the cold and standard phase was 79. 91 and 69. 20, respectively.
Hemodialysis significantly improved URR levels (P <0. 001).
Conclusion: Cold hemodialysis significantly improves the adequacy of hemodialysis.