THE EFFECT OF PETHIDINE ON PHYSIOLOGICAL PARAMETERS OF NEWBORNS OF NON-EMERGENCY CESAREAN SECTION MOTHERS BY SPINAL ANESTHESIA IN AMIR AL-MOMENIN HOSPITAL OF GHERASH IN 2017

One of the challenges of the cesarean section is the control of pain in the mother.
The role of pethidine in neonatal-related complications is not clear.
The aim of this study was to investigate the effect of pethidine on physiological parameters of newborns
of non-emergency cesarean section mothers by spinal anesthesia in Amir al-Momenin Hospital of
Gherash in 2017.
Materials & Methods: This experimental clinical trial study was performed on 116 neonates whose
mothers underwent non-emergency cesarean section by spinal anesthesia. Study subjects were randomly
assigned into intervention and control groups with binary blocks design. Intervention consisted of
routine care (100 mg of diclofenac suppository) in the control group and the single dose of 100 mg
pethidine was given intravenously in the experimental group by the anesthesiologist. The physiological
parameters of neonates in both groups were recorded by the researcher and her assistant within 48 hours
of hospitalization.
Results: Despite the fact that the mean heart rate of neonates in the experimental group (141.12) within
the first 48 hours after birth was higher than that of the control group (40.41), the results of the
independent t-test did not show any significant difference between the two groups in terms of the mean
of neonatal heart rate (p = 0.354) and the percentage of arterial blood oxygen (p = 0.580). The mean of
respiratory rate within the 48 hours after birth in the control group was higher than that of the pethidine
group (p = 116). The mean of body temperature of infants in the two groups was negligible (p = 0.335).
Conclusion: The single dose of pethidine had no significant effect on the physiological parameters of
newborns of non-emergency cesarean mothers by spinal method